Foto Pythons' metabolism features may suggest new ways to fight excess weight
It is about a compound called para-tyramine-O-sulfate (pTOS), found in the blood of pythons after eating. The researchers found that the level of this molecule increases sharply immediately after eating and is associated with the satiety signal, which is transmitted to the brain, writes euronews. Interestingly, a similar process occurs in humans, although to a much lesser extent.
The mechanism is as follows: intestinal bacteria convert the amino acid tyrosine into tyramine, after which the liver turns it into pTOS. The molecule then travels to the brain and reduces the feeling of hunger. This discovery emphasizes the important role of the gut microbiota in the regulation of appetite and metabolism.
Experiments in mice have shown that administration of pTOS leads to reduced food intake and weight loss without noticeable side effects. Unlike current weight loss drugs, which can cause nausea and digestive problems, this mechanism potentially acts in a gentler and more natural way.
However, the study is in its early stages. Scientists do not yet know how effectively pTOS will work in humans, especially those with type 2 diabetes or metabolic disorders. It is suspected that in such cases, the satiety signal may be weakened.
The discovery offers the hope of creating new methods to combat obesity based on the body’s natural processes. In the future, this may lead to the development of safer and more effective ways to control weight.
